Human growth hormone (HGH) functions all throughout a man’s life. The anterior part of the pituitary gland, which produces HGH, continuously secretes HGH even as people grow older. However, the amount of HGH secretion decreases as people exceeds the puberty years. Adults are prone to many diseases because their immune system weakens thus affecting the whole body system. Adults, like children, are also susceptible to HGH diseases.
HGH diseases are mainly of two kinds; deficiency of HGH and excessive HGH. HGH diseases in adults have two general categories;
1.) An adult who had an HGH disease as a child and continues to have the disease
2.)An adult who have gotten the HGH disease after youth
One of the HGH diseases that an adult has is Adult Growth Hormone Deficiency (AGHD). This disease is a disorder which is brought by many factors including the malfunction of the pituitary gland. AGHD has many symptoms namely; abnormal body composition, increased fat mass, decreased lean muscle mass, and decrease in physical power and endurance. AGHD can also bring negative effects to the heart. AGHD, when not treated, leads to morbidity and frequent cardiovascular attacks. In the last 15 years, it has been recognized that growth hormone deficiency (GHD) can happen in adults.
Unlike in cases of children where GHD is easily determined, AGHD is hard to identify because of the lack of growth parameters and effects of other diseases that the patient acquire because of old age. Hence AGHD is determined by conducting a test. The growth hormone stimulation test (GHST) is usually used to determine HGH diseases. GHST measures the ability of the pituitary gland to produce HGH. However, the accuracy of this test was questioned because of test variability and the uniqueness of the physiology of every individual. These factors together with the admittance that IGF-I is significant to HGH makes the analysis of AGHD difficult and diverse.